Seattle Mariners Lead Houston Astros 8-5 in Head-to-Head Matchups (2025)

MLB6-7-0 ATS (46.15%)Data through 2025-09-21

Mariners vs Astros Betting Record — 2025

Against the Spread
6-7-0
Win %
46.15%
ROI
+6.42%
Units
+0.8
Moneyline
8-5-0
Win %
61.54%
ROI
+12.56%
Units
+1.6
Over Rate
6-5-2
Win %
54.55%
ROI
+5.22%
Units
+0.6

From the Other Side — Astros vs Mariners

Against the Spread
7-6-0
Win %
53.85%
ROI
-15.44%
Units
-2.0
Moneyline
5-8-0
Win %
38.46%
ROI
-18.75%
Units
-2.4
Over Rate
6-5-2
Win %
54.55%
ROI
+5.22%
Units
+0.6

Venue Splits

Mariners Home
2-4-0 ATS
33.33% • -31.08%
4-2-0 ML (66.67%)
Astros Home
3-4-0 ATS
42.86% • -29.41%
3-4-0 ML (42.86%)

Scoring Averages

Mariners
4.3
PPG
4.2
allowed
Total
8.5
Avg
13
games
Astros
4.2
PPG
4.3
allowed

Recent Matchups (2025)

DateScoreATSMLO/U
09/21W 3-7WO
09/20W 4-6WO
09/19W 0-4WU
07/20L 3-11LO
07/19W 7-6WO
07/18W 6-1WP
05/25L 5-3LU
05/24L 2-1LU
05/23W 3-5WU
05/22L 9-2LO
04/09W 7-6WO
04/08L 1-2LU
04/07W 4-3WP

Frequently Asked Questions

What is the Seattle Mariners vs Houston Astros all-time record?
The Seattle Mariners are 8-5 against the Houston Astros in 2025 in head-to-head matchups.
What is the Seattle Mariners ATS record vs the Houston Astros?
The Seattle Mariners are 6-7-0 against the spread vs the Houston Astros in 2025 on DraftKings, with +6.42% ROI.
Do Seattle Mariners vs Houston Astros games go over or under?
Seattle Mariners vs Houston Astros games average 8.5 total points in 2025. The Over has hit 54.55% of the time.

More Mariners Matchups

Head-to-head betting record for Seattle Mariners vs Houston Astros in the 2025 season on LineTerminal. The Mariners are 8-5 straight up against the Astros and 6-7-0 against the spread (46.15% cover rate, +6.42% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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