CardinalsAway0
CubsHome2Run lineCoverFav -1.5
MoneylineWin
TotalUnder7
MLB · Head to head
Cubs vs Cardinals
2025 seasonLast meeting Sep 28, 2025
Betting comparison
2025
Cubs
13 bets8-5-0Wins · Losses · Pushes
- Win rate
- 61.54%
- ROI
- +34.66%
- Units
- +4.51u
Cardinals
13 bets5-8-0Wins · Losses · Pushes
- Win rate
- 38.46%
- ROI
- -35.96%
- Units
- -4.67u
Closing lines · Flat 1u per bet · Methodology
Scoring per game
Average runsCubs6.2
Cardinals3.1
Combined9.2
Recent meetings
Bet results from the Cubs perspective. Spread values show the favorite’s closing line.
CardinalsAway0CubsHome2CardinalsAway3CubsHome7Run lineCoverFav -1.5
MoneylineWin
TotalOver9.5
CardinalsAway1CubsHome12Run lineCoverFav -1.5
MoneylineWin
TotalOver9
CubsAway2CardinalsHome3Run lineMissFav -1.5
MoneylineLoss
TotalUnder7.5
CubsAway9CardinalsHome1Run lineCoverFav -1.5
MoneylineWin
TotalOver9
More Cubs matchups
About this matchup
What is the Chicago Cubs vs St. Louis Cardinals 2025 record?
The Chicago Cubs are 8-5 against the St. Louis Cardinals in 2025 in head-to-head matchups.
What is the Chicago Cubs ATS record vs the St. Louis Cardinals?
The Chicago Cubs are 8-5-0 against the spread vs the St. Louis Cardinals in 2025 on DraftKings, with +34.66% ROI.
Do Chicago Cubs vs St. Louis Cardinals games go over or under?
Chicago Cubs vs St. Louis Cardinals games average 9.2 total runs in 2025. The Over has hit 61.54% of the time.