Inside Edge
Cubs vs Cardinals Betting Record — 2025
Against the Spread
8-5-0
Win %
61.54%
ROI
+34.66%
Units
+4.5
Moneyline
8-5-0
Win %
61.54%
ROI
+0.62%
Units
+0.1
Over Rate
8-5-0
Win %
61.54%
ROI
+16.28%
Units
+2.1
From the Other Side — Cardinals vs Cubs
Against the Spread
5-8-0
Win %
38.46%
ROI
-35.96%
Units
-4.7
Moneyline
5-8-0
Win %
38.46%
ROI
-17.7%
Units
-2.3
Over Rate
8-5-0
Win %
61.54%
ROI
+16.28%
Units
+2.1
Venue Splits
Cubs Home
5-1-0 ATS
83.33% • +81.6%
5-1-0 ML (83.33%)
Cardinals Home
4-3-0 ATS
57.14% • -5.13%
4-3-0 ML (57.14%)
Scoring Averages
Cubs
6.2
PPG
3.1
allowed
Total
9.2
Avg
13
games
Cardinals
3.1
PPG
6.2
allowed
Recent Matchups (2025)
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 09/282025-09-28 | W 2-0 | ✓ | W | U |
| 09/272025-09-27 | W 7-3 | ✓ | W | O |
| 09/262025-09-26 | W 12-1 | ✓ | W | O |
| 08/102025-08-10 | L 3-2 | ✗ | L | U |
| 08/092025-08-09 | W 1-9 | ✓ | W | O |
| 08/082025-08-08 | L 5-0 | ✗ | L | U |
| 07/062025-07-06 | W 11-0 | ✓ | W | O |
| 07/052025-07-05 | L 6-8 | ✗ | L | O |
| 07/042025-07-04 | W 11-3 | ✓ | W | O |
| 06/262025-06-26 | W 0-3 | ✓ | W | U |
| 06/252025-06-25 | W 0-8 | ✓ | W | U |
| 06/242025-06-24 | L 8-7 | ✗ | L | O |
| 06/232025-06-23 | L 8-2 | ✗ | L | O |
Frequently Asked Questions
What is the Chicago Cubs vs St. Louis Cardinals all-time record?
The Chicago Cubs are 8-5 against the St. Louis Cardinals in 2025 in head-to-head matchups.
What is the Chicago Cubs ATS record vs the St. Louis Cardinals?
The Chicago Cubs are 8-5-0 against the spread vs the St. Louis Cardinals in 2025 on DraftKings, with +34.66% ROI.
Do Chicago Cubs vs St. Louis Cardinals games go over or under?
Chicago Cubs vs St. Louis Cardinals games average 9.2 total points in 2025. The Over has hit 61.54% of the time.
