49ersAway32
SeahawksHome29SpreadMissFav -3
MoneylineLoss
TotalOver46.5
NFL · Head to head
Seahawks vs 49ers
All recorded seasonsLast meeting Oct 11, 2026
Betting comparison
All seasons
Seahawks
15 bets7-8-0Wins · Losses · Pushes
- Win rate
- 46.67%
- ROI
- -11.31%
- Units
- -1.7u
49ers
15 bets8-7-0Wins · Losses · Pushes
- Win rate
- 53.33%
- ROI
- +0.64%
- Units
- +0.1u
Closing lines · Flat 1u per bet · Methodology
Scoring per game
Average pointsSeahawks22.2
49ers23.5
Combined45.7
Recent meetings
Bet results from the Seahawks perspective. Spread values show the favorite’s closing line.
49ersAway32SeahawksHome2949ersAway6SeahawksHome41SpreadCoverFav -7
MoneylineWin
TotalOver44.5
SeahawksAway1349ersHome3SpreadCoverFav -2.5
MoneylineWin
TotalUnder48.5
49ersAway17SeahawksHome13SpreadMissFav -2.5
MoneylineLoss
TotalUnder43.5
SeahawksAway2049ersHome17SpreadCoverFav -6
MoneylineWin
TotalUnder48.5
More Seahawks matchups
About this matchup
What is the Seattle Seahawks vs San Francisco 49ers all-time record?
The Seattle Seahawks are 7-8 against the San Francisco 49ers in head-to-head matchups.
What is the Seattle Seahawks ATS record vs the San Francisco 49ers?
The Seattle Seahawks are 7-8-0 against the spread vs the San Francisco 49ers on DraftKings, with -11.31% ROI.
Do Seattle Seahawks vs San Francisco 49ers games go over or under?
Seattle Seahawks vs San Francisco 49ers games average 45.7 total points. The Over has hit 53.33% of the time.