Buffalo Bills and New England Patriots Tied 1-1 Head-to-Head (2025-26)

NFL1-1-0 ATS (50%)Updated December 14, 2025

The Buffalo Bills are 1-1 against the New England Patriots in 2025-26 in head-to-head matchups, going 1-1-0 ATS (50% cover rate) with -4.55% ROI. Games average 54.5 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NFL box scores.

See methodology.

Bills vs Patriots Betting Record — 2025-26

Against the Spread

1-1-0

Win %

50%

ROI

-4.55%

Units

-0.1

Moneyline

1-1-0

Win %

50%

ROI

-14.79%

Units

-0.3

Over Rate

1-1-0

Win %

50%

ROI

-6.52%

Units

-0.1

From the Other Side — Patriots vs Bills

Against the Spread

1-1-0

Win %

50%

ROI

-2.38%

Units

-0.1

Moneyline

1-1-0

Win %

50%

ROI

+105%

Units

+2.1

Over Rate

1-1-0

Win %

50%

ROI

-6.52%

Units

-0.1

Venue Splits

Bills Home

0-1-0 ATS

0% • -100%

0-1-0 ML (0%)

Patriots Home

0-1-0 ATS

0% • -100%

0-1-0 ML (0%)

Scoring Averages

Bills

27.5

PPG

allowed

Total

54.5

Avg

games

Patriots

PPG

27.5

allowed

Recent Matchups (2025-26)

Date	Matchup	Score	Spread	ATS	ML	O/U
12/142025-12-14	Bills @ Patriots	W 31-35	-2.5	✓	W	O
10/052025-10-05	Patriots @ Bills	L 20-23	-7.5	✗	L	U

Frequently Asked Questions

What is the Buffalo Bills vs New England Patriots 2025-26 record?

The Buffalo Bills are 1-1 against the New England Patriots in 2025-26 in head-to-head matchups.

What is the Buffalo Bills ATS record vs the New England Patriots?

The Buffalo Bills are 1-1-0 against the spread vs the New England Patriots in 2025-26 on DraftKings, with -4.55% ROI.

Do Buffalo Bills vs New England Patriots games go over or under?

Buffalo Bills vs New England Patriots games average 54.5 total points in 2025-26. The Over has hit 50% of the time.

More Bills Matchups

vs Dolphins

vs Jets

See from Patriots perspective

Head-to-head betting record for Buffalo Bills vs New England Patriots in the 2025-26 season on LineTerminal. The Bills are 1-1 straight up against the Patriots and 1-1-0 against the spread (50% cover rate, -4.55% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.