PatriotsAway29
BillsHome26SpreadMissFav -7
MoneylineLoss
TotalOver49.5
NFL · Head to head
Bills vs Patriots
All recorded seasonsLast meeting Oct 4, 2026
Betting comparison
All seasons
Bills
14 bets6-8-0Wins · Losses · Pushes
- Win rate
- 42.86%
- ROI
- -18.1%
- Units
- -2.53u
Patriots
14 bets8-6-0Wins · Losses · Pushes
- Win rate
- 57.14%
- ROI
- +9.71%
- Units
- +1.36u
Closing lines · Flat 1u per bet · Methodology
Scoring per game
Average pointsBills27.4
Patriots20.9
Combined48.3
Recent meetings
Bet results from the Bills perspective. Spread values show the favorite’s closing line.
PatriotsAway29BillsHome26BillsAway35PatriotsHome31SpreadCoverFav -2.5
MoneylineWin
TotalOver49.5
PatriotsAway23BillsHome20SpreadMissFav -7.5
MoneylineLoss
TotalUnder49.5
BillsAway16PatriotsHome23SpreadMissFav -3
MoneylineLoss
TotalOver36.5
PatriotsAway21BillsHome24SpreadMissFav -14
MoneylineWin
TotalUnder48
More Bills matchups
About this matchup
What is the Buffalo Bills vs New England Patriots all-time record?
The Buffalo Bills are 9-5 against the New England Patriots in head-to-head matchups.
What is the Buffalo Bills ATS record vs the New England Patriots?
The Buffalo Bills are 6-8-0 against the spread vs the New England Patriots on DraftKings, with -18.1% ROI.
Do Buffalo Bills vs New England Patriots games go over or under?
Buffalo Bills vs New England Patriots games average 48.3 total points. The Over has hit 69.23% of the time.