Patriots vs Bills Betting Record
Against the Spread
7-6-0
Win %
53.85%
ROI
+3.46%
Units
+0.5
Moneyline
4-9-0
Win %
30.77%
ROI
-1%
Units
-0.1
Over Rate
8-4-1
Win %
66.67%
ROI
+26.01%
Units
+3.1
From the Other Side — Bills vs Patriots
Against the Spread
6-7-0
Win %
46.15%
ROI
-11.8%
Units
-1.5
Moneyline
9-4-0
Win %
69.23%
ROI
-0.71%
Units
-0.1
Over Rate
8-4-1
Win %
66.67%
ROI
+26.01%
Units
+3.1
Venue Splits
Patriots Home
2-4-0 ATS
33.33% • -35.64%
2-4-0 ML (33.33%)
Bills Home
2-5-0 ATS
28.57% • -44.84%
5-2-0 ML (71.43%)
Scoring Averages
Patriots
20.2
PPG
27.5
allowed
Total
47.8
Avg
13
games
Bills
27.5
PPG
20.2
allowed
Recent Matchups
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 12/142025-12-14 | L 31-35 | ✗ | L | O |
| 10/052025-10-05 | W 20-23 | ✓ | W | U |
| 01/052025-01-05 | W 23-16 | ✓ | W | O |
| 12/222024-12-22 | L 24-21 | ✓ | L | U |
| 12/312023-12-31 | L 27-21 | ✓ | L | O |
| 10/222023-10-22 | W 29-25 | ✓ | W | O |
| 01/082023-01-08 | L 35-23 | ✗ | L | O |
| 12/012022-12-01 | L 10-24 | ✗ | L | U |
| 01/152022-01-15 | L 47-17 | ✗ | L | O |
| 12/262021-12-26 | L 21-33 | ✗ | L | O |
| 12/062021-12-06 | W 10-14 | ✓ | W | U |
| 12/282020-12-28 | L 9-38 | ✗ | L | P |
| 11/012020-11-01 | L 24-21 | ✓ | L | O |
Frequently Asked Questions
What is the New England Patriots vs Buffalo Bills all-time record?
The New England Patriots are 4-9 against the Buffalo Bills in head-to-head matchups.
What is the New England Patriots ATS record vs the Buffalo Bills?
The New England Patriots are 7-6-0 against the spread vs the Buffalo Bills on DraftKings, with +3.46% ROI.
Do New England Patriots vs Buffalo Bills games go over or under?
New England Patriots vs Buffalo Bills games average 47.8 total points. The Over has hit 66.67% of the time.
Inside Edge