Colorado Buffaloes Lead Iowa State Cyclones 1-0 in Head-to-Head Matchups (2025-26)

NCAAF0-1-0 ATS (0%)Updated October 11, 2025

The Iowa State Cyclones are 0-1 against the Colorado Buffaloes in 2025-26 in head-to-head matchups, going 0-1-0 ATS (0% cover rate) with -100% ROI. Games average 41 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Cyclones vs Buffaloes Betting Record — 2025-26

Against the Spread

0-1-0

Win %

ROI

-100%

Units

-1.0

Moneyline

0-1-0

Win %

ROI

-100%

Units

-1.0

Over Rate

0-1-0

Win %

ROI

-100%

Units

-1.0

From the Other Side — Buffaloes vs Cyclones

Against the Spread

1-0-0

Win %

100%

ROI

+90.91%

Units

+0.9

Moneyline

1-0-0

Win %

100%

ROI

+124%

Units

+1.2

Over Rate

0-1-0

Win %

ROI

-100%

Units

-1.0

Venue Splits

Cyclones Home

Buffaloes Home

1-0-0 ATS

100% • +90.91%

1-0-0 ML (100%)

Scoring Averages

Cyclones

PPG

allowed

Total

Avg

games

Buffaloes

PPG

allowed

Recent Matchups (2025-26)

Date	Matchup	Score	Spread	ATS	ML	O/U
10/112025-10-11	Cyclones @ Buffaloes	L 24-17	-3	✗	L	U

Frequently Asked Questions

What is the Iowa State Cyclones vs Colorado Buffaloes 2025-26 record?

The Iowa State Cyclones are 0-1 against the Colorado Buffaloes in 2025-26 in head-to-head matchups.

What is the Iowa State Cyclones ATS record vs the Colorado Buffaloes?

The Iowa State Cyclones are 0-1-0 against the spread vs the Colorado Buffaloes in 2025-26 on DraftKings, with -100% ROI.

Do Iowa State Cyclones vs Colorado Buffaloes games go over or under?

Iowa State Cyclones vs Colorado Buffaloes games average 41 total points in 2025-26. The Over has hit 0% of the time.

More Cyclones Matchups

See from Buffaloes perspective

Head-to-head betting record for Iowa State Cyclones vs Colorado Buffaloes in the 2025-26 season on LineTerminal. The Cyclones are 0-1 straight up against the Buffaloes and 0-1-0 against the spread (0% cover rate, -100% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.