Indiana Hoosiers Lead Michigan State Spartans 3-1 in Head-to-Head Matchups

NCAAF2-2-0 ATS (50%)Updated October 18, 2025

The Indiana Hoosiers are 3-1 against the Michigan State Spartans in head-to-head matchups, going 2-2-0 ATS (50% cover rate) with -4.55% ROI. Games average 55.8 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Hoosiers vs Spartans Betting Record

Against the Spread

2-2-0

Win %

50%

ROI

-4.55%

Units

-0.2

Moneyline

3-1-0

Win %

75%

ROI

+71.39%

Units

+2.9

Over Rate

3-1-0

Win %

75%

ROI

+42.61%

Units

+1.7

From the Other Side — Spartans vs Hoosiers

Against the Spread

2-2-0

Win %

50%

ROI

-4.53%

Units

-0.2

Moneyline

1-3-0

Win %

25%

ROI

-37.5%

Units

-1.5

Over Rate

3-1-0

Win %

75%

ROI

+42.61%

Units

+1.7

Venue Splits

Hoosiers Home

0-2-0 ATS

0% • -100%

1-1-0 ML (50%)

Spartans Home

0-2-0 ATS

0% • -100%

0-2-0 ML (0%)

Scoring Averages

Hoosiers

36.3

PPG

19.5

allowed

Total

55.8

Avg

games

Spartans

19.5

PPG

36.3

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
10/182025-10-18	Spartans @ Hoosiers	W 38-13	-26.5	✗	W	O
11/022024-11-02	Hoosiers @ Spartans	W 10-47	-7.5	✓	W	O
11/182023-11-18	Spartans @ Hoosiers	L 21-24	-3.5	✗	L	U
11/192022-11-19	Hoosiers @ Spartans	W 31-39	-12	✓	W	O

Frequently Asked Questions

What is the Indiana Hoosiers vs Michigan State Spartans all-time record?

The Indiana Hoosiers are 3-1 against the Michigan State Spartans in head-to-head matchups.

What is the Indiana Hoosiers ATS record vs the Michigan State Spartans?

The Indiana Hoosiers are 2-2-0 against the spread vs the Michigan State Spartans on DraftKings, with -4.55% ROI.

Do Indiana Hoosiers vs Michigan State Spartans games go over or under?

Indiana Hoosiers vs Michigan State Spartans games average 55.8 total points. The Over has hit 75% of the time.

More Hoosiers Matchups

See from Spartans perspective

Head-to-head betting record for Indiana Hoosiers vs Michigan State Spartans on LineTerminal. The Hoosiers are 3-1 straight up against the Spartans and 2-2-0 against the spread (50% cover rate, -4.55% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.