Louisville CardinalsAway100
Pittsburgh PanthersHome59SpreadMissFav -7.5
MoneylineLoss
TotalOver152.5
NCAAB · Head to head
Pittsburgh Panthers vs Louisville Cardinals
All recorded seasonsLast meeting Jan 17, 2026
Betting comparison
All seasons
Pittsburgh Panthers
8 bets5-3-0Wins · Losses · Pushes
- Win rate
- 62.5%
- ROI
- +17.97%
- Units
- +1.44u
Louisville Cardinals
8 bets3-5-0Wins · Losses · Pushes
- Win rate
- 37.5%
- ROI
- -27.33%
- Units
- -2.19u
Closing lines · Flat 1u per bet · Methodology
Scoring per game
Average pointsPittsburgh Panthers75.6
Louisville Cardinals69.3
Combined144.9
Recent meetings
Bet results from the Pittsburgh Panthers perspective. Spread values show the favorite’s closing line.
Louisville CardinalsAway100Pittsburgh PanthersHome59Pittsburgh PanthersAway68Louisville CardinalsHome79SpreadMissFav -10.5
MoneylineLoss
TotalUnder150.5
Louisville CardinalsAway82Pittsburgh PanthersHome78SpreadMissFav -3.5
MoneylineLoss
TotalOver149.5
Louisville CardinalsAway59Pittsburgh PanthersHome86SpreadCoverFav -12.5
MoneylineWin
TotalUnder150.5
Pittsburgh PanthersAway83Louisville CardinalsHome70SpreadCoverFav -8.5
MoneylineWin
TotalOver144.5
More Pittsburgh Panthers matchups
About this matchup
What is the Pittsburgh Panthers vs Louisville Cardinals all-time record?
The Pittsburgh Panthers are 5-3 against the Louisville Cardinals in head-to-head matchups.
What is the Pittsburgh Panthers ATS record vs the Louisville Cardinals?
The Pittsburgh Panthers are 5-3-0 against the spread vs the Louisville Cardinals on DraftKings, with +17.97% ROI.
Do Pittsburgh Panthers vs Louisville Cardinals games go over or under?
Pittsburgh Panthers vs Louisville Cardinals games average 144.9 total points. The Over has hit 50% of the time.