Louisville CardinalsAway100
Pittsburgh PanthersHome59SpreadCoverFav -7.5
MoneylineWin
TotalOver152.5
NCAAB · Head to head
Louisville Cardinals vs Pittsburgh Panthers
All recorded seasonsLast meeting Jan 17, 2026
Betting comparison
All seasons
Louisville Cardinals
8 bets3-5-0Wins · Losses · Pushes
- Win rate
- 37.5%
- ROI
- -27.33%
- Units
- -2.19u
Pittsburgh Panthers
8 bets5-3-0Wins · Losses · Pushes
- Win rate
- 62.5%
- ROI
- +17.97%
- Units
- +1.44u
Closing lines · Flat 1u per bet · Methodology
Scoring per game
Average pointsLouisville Cardinals69.3
Pittsburgh Panthers75.6
Combined144.9
Recent meetings
Bet results from the Louisville Cardinals perspective. Spread values show the favorite’s closing line.
Louisville CardinalsAway100Pittsburgh PanthersHome59Pittsburgh PanthersAway68Louisville CardinalsHome79SpreadCoverFav -10.5
MoneylineWin
TotalUnder150.5
Louisville CardinalsAway82Pittsburgh PanthersHome78SpreadCoverFav -3.5
MoneylineWin
TotalOver149.5
Louisville CardinalsAway59Pittsburgh PanthersHome86SpreadMissFav -12.5
MoneylineLoss
TotalUnder150.5
Pittsburgh PanthersAway83Louisville CardinalsHome70SpreadMissFav -8.5
MoneylineLoss
TotalOver144.5
More Louisville Cardinals matchups
About this matchup
What is the Louisville Cardinals vs Pittsburgh Panthers all-time record?
The Louisville Cardinals are 3-5 against the Pittsburgh Panthers in head-to-head matchups.
What is the Louisville Cardinals ATS record vs the Pittsburgh Panthers?
The Louisville Cardinals are 3-5-0 against the spread vs the Pittsburgh Panthers on DraftKings, with -27.33% ROI.
Do Louisville Cardinals vs Pittsburgh Panthers games go over or under?
Louisville Cardinals vs Pittsburgh Panthers games average 144.9 total points. The Over has hit 50% of the time.