San Diego Padres Lead San Francisco Giants 54-35 in Head-to-Head Matchups

MLB29-45-0 ATS (39.19%)

The San Francisco Giants are 35-54 against the San Diego Padres in head-to-head matchups, going 29-45-0 ATS (39.19% cover rate) with -29.28% ROI. Games average 8.8 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official MLB box scores.

See methodology.

Giants vs Padres Betting Record

Against the Spread
29-45-0
Win %
39.19%
ROI
-29.28%
Units
-21.7
Moneyline
34-53-1
Win %
39.08%
ROI
-20.84%
Units
-18.1
Over Rate
39-34-1
Win %
53.42%
ROI
+1.67%
Units
+1.2

From the Other Side — Padres vs Giants

Against the Spread
45-29-0
Win %
60.81%
ROI
+22.75%
Units
+16.8
Moneyline
53-34-1
Win %
60.92%
ROI
+11.68%
Units
+10.2
Over Rate
39-34-1
Win %
53.42%
ROI
+1.67%
Units
+1.2

Venue Splits

Giants Home
16-23-0 ATS
41.03% • -32.01%
19-28-0 ML (40.43%)
Padres Home
22-13-0 ATS
62.86% • +31.8%
25-15-1 ML (62.5%)

Scoring Averages

Giants
3.9
PPG
4.9
allowed
Total
8.8
Avg
89
games
Padres
4.9
PPG
3.9
allowed

Recent Matchups

DateScoreATSMLO/U
05/06L 1-5LU
05/05L 5-10LO
05/04W 3-2WU
04/01L 7-1LP
03/31W 3-9WO
03/30W 2-3WU
08/21L 8-4LO
08/20L 8-1LO
08/19L 5-1LU
08/18W 3-4WU
08/13L 1-11LO
08/12L 1-5LU
08/11L 1-4LU
06/05W 3-2WU
06/04W 6-5WO
06/03L 2-3LU
06/02L 0-1LU
04/30L 5-3LO
04/29L 7-4LO
09/15L 3-4LU

Frequently Asked Questions

What is the San Francisco Giants vs San Diego Padres all-time record?
The San Francisco Giants are 35-54 against the San Diego Padres in head-to-head matchups.
What is the San Francisco Giants ATS record vs the San Diego Padres?
The San Francisco Giants are 29-45-0 against the spread vs the San Diego Padres on DraftKings, with -29.28% ROI.
Do San Francisco Giants vs San Diego Padres games go over or under?
San Francisco Giants vs San Diego Padres games average 8.8 total points. The Over has hit 53.42% of the time.

More Giants Matchups

Head-to-head betting record for San Francisco Giants vs San Diego Padres on LineTerminal. The Giants are 35-54 straight up against the Padres and 29-45-0 against the spread (39.19% cover rate, -29.28% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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