San Francisco Giants vs San Diego Padres: 34-52 H2H, 28-43-0 ATS

Giants vs Padres Betting Record

Against the Spread

28-43-0

Win %

39.44%

ROI

-28.65%

Units

-20.3

Moneyline

33-51-1

Win %

39.29%

ROI

-20.49%

Units

-17.2

Over Rate

38-32-1

Win %

54.29%

ROI

+3.27%

Units

+2.3

From the Other Side — Padres vs Giants

Against the Spread

43-28-0

Win %

60.56%

ROI

+22.06%

Units

+15.7

Moneyline

51-33-1

Win %

60.71%

ROI

+10.65%

Units

+8.9

Over Rate

38-32-1

Win %

54.29%

ROI

+3.27%

Units

+2.3

Venue Splits

Giants Home

15-21-0 ATS

41.67% • -30.98%

18-26-0 ML (40.91%)

Padres Home

22-13-0 ATS

62.86% • +31.8%

25-15-1 ML (62.5%)

Scoring Averages

Giants

3.9

PPG

4.8

allowed

Total

8.8

Avg

games

Padres

4.8

PPG

3.9

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
04/012026-04-01	Giants @ Padres	L 7-1	-1.5	✗	L	P
03/312026-03-31	Giants @ Padres	W 3-9	-1.5	✓	W	O
03/302026-03-30	Giants @ Padres	W 2-3	-1.5	✗	W	U
08/212025-08-21	Giants @ Padres	L 8-4	-1.5	✗	L	O
08/202025-08-20	Giants @ Padres	L 8-1	-1.5	✗	L	O
08/192025-08-19	Giants @ Padres	L 5-1	-1.5	✗	L	U
08/182025-08-18	Giants @ Padres	W 3-4	-1.5	✓	W	U
08/132025-08-13	Padres @ Giants	L 1-11	-1.5	✗	L	O
08/122025-08-12	Padres @ Giants	L 1-5	-1.5	✗	L	U
08/112025-08-11	Padres @ Giants	L 1-4	-1.5	✗	L	U
06/052025-06-05	Padres @ Giants	W 3-2	-1.5	✓	W	U
06/042025-06-04	Padres @ Giants	W 6-5	-1.5	✓	W	O
06/032025-06-03	Padres @ Giants	L 2-3	-1.5	✗	L	U
06/022025-06-02	Padres @ Giants	L 0-1	-1.5	✗	L	U
04/302025-04-30	Giants @ Padres	L 5-3	-1.5	✗	L	O
04/292025-04-29	Giants @ Padres	L 7-4	-1.5	✗	L	O
09/152024-09-15	Padres @ Giants	L 3-4	-1.5	✓	L	U
09/142024-09-14	Padres @ Giants	L 0-8	-1.5	✗	L	O
09/132024-09-13	Padres @ Giants	L 0-5	-1.5	✗	L	U
09/082024-09-08	Giants @ Padres	W 6-7	-1.5	✓	W	O

Frequently Asked Questions

What is the San Francisco Giants vs San Diego Padres all-time record?

The San Francisco Giants are 34-52 against the San Diego Padres in head-to-head matchups.

What is the San Francisco Giants ATS record vs the San Diego Padres?

The San Francisco Giants are 28-43-0 against the spread vs the San Diego Padres on DraftKings, with -28.65% ROI.

Do San Francisco Giants vs San Diego Padres games go over or under?

San Francisco Giants vs San Diego Padres games average 8.8 total points. The Over has hit 54.29% of the time.

More Giants Matchups

vs Diamondbacks

vs Rockies

vs Dodgers

See from Padres perspective