San Diego Padres Lead San Francisco Giants 54-35 in Head-to-Head Matchups

MLB45-29-0 ATS (60.81%)

The San Diego Padres are 54-35 against the San Francisco Giants in head-to-head matchups, going 45-29-0 ATS (60.81% cover rate) with +22.75% ROI. Games average 8.8 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official MLB box scores.

See methodology.

Padres vs Giants Betting Record

Against the Spread
45-29-0
Win %
60.81%
ROI
+22.75%
Units
+16.8
Moneyline
53-34-1
Win %
60.92%
ROI
+11.68%
Units
+10.2
Over Rate
39-34-1
Win %
53.42%
ROI
+1.67%
Units
+1.2

From the Other Side — Giants vs Padres

Against the Spread
29-45-0
Win %
39.19%
ROI
-29.28%
Units
-21.7
Moneyline
34-53-1
Win %
39.08%
ROI
-20.84%
Units
-18.1
Over Rate
39-34-1
Win %
53.42%
ROI
+1.67%
Units
+1.2

Venue Splits

Padres Home
22-13-0 ATS
62.86% • +31.8%
25-15-1 ML (62.5%)
Giants Home
16-23-0 ATS
41.03% • -32.01%
19-28-0 ML (40.43%)

Scoring Averages

Padres
4.9
PPG
3.9
allowed
Total
8.8
Avg
89
games
Giants
3.9
PPG
4.9
allowed

Recent Matchups

DateScoreATSMLO/U
05/06W 1-5WU
05/05W 5-10WO
05/04L 3-2LU
04/01W 7-1WP
03/31L 3-9LO
03/30L 2-3LU
08/21W 8-4WO
08/20W 8-1WO
08/19W 5-1WU
08/18L 3-4LU
08/13W 1-11WO
08/12W 1-5WU
08/11W 1-4WU
06/05L 3-2LU
06/04L 6-5LO
06/03W 2-3WU
06/02W 0-1WU
04/30W 5-3WO
04/29W 7-4WO
09/15W 3-4WU

Frequently Asked Questions

What is the San Diego Padres vs San Francisco Giants all-time record?
The San Diego Padres are 54-35 against the San Francisco Giants in head-to-head matchups.
What is the San Diego Padres ATS record vs the San Francisco Giants?
The San Diego Padres are 45-29-0 against the spread vs the San Francisco Giants on DraftKings, with +22.75% ROI.
Do San Diego Padres vs San Francisco Giants games go over or under?
San Diego Padres vs San Francisco Giants games average 8.8 total points. The Over has hit 53.42% of the time.

More Padres Matchups

Head-to-head betting record for San Diego Padres vs San Francisco Giants on LineTerminal. The Padres are 54-35 straight up against the Giants and 45-29-0 against the spread (60.81% cover rate, +22.75% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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