Houston Astros Lead Seattle Mariners 15-7 in Head-to-Head Matchups (2022)

MLB11-11-0 ATS (50%)Data through 2022-10-15

Astros vs Mariners Betting Record — 2022

Against the Spread
11-11-0
Win %
50%
ROI
+11.49%
Units
+2.5
Moneyline
15-7-0
Win %
68.18%
ROI
+12.69%
Units
+2.8
Over Rate
9-13-0
Win %
40.91%
ROI
-23.4%
Units
-5.2

From the Other Side — Mariners vs Astros

Against the Spread
11-11-0
Win %
50%
ROI
-14.99%
Units
-3.3
Moneyline
7-15-0
Win %
31.82%
ROI
-27.45%
Units
-6.0
Over Rate
9-13-0
Win %
40.91%
ROI
-23.4%
Units
-5.2

Venue Splits

Astros Home
7-5-0 ATS
58.33% • +28.57%
9-3-0 ML (75%)
Mariners Home
6-4-0 ATS
60% • +1.4%
4-6-0 ML (40%)

Scoring Averages

Astros
3.9
PPG
3.4
allowed
Total
7.3
Avg
22
games
Mariners
3.4
PPG
3.9
allowed

Recent Matchups (2022)

DateScoreATSMLO/U
10/15W 0-1WU
10/13W 4-2WU
10/11W 8-7WO
07/31W 3-2WU
07/30L 4-5LO
07/29W 11-1WO
07/28W 4-2WU
07/24W 5-8WO
07/23W 1-3WU
07/22W 2-5WU
06/08L 3-6LO
06/07W 4-1WU
06/06L 4-7LO
05/29W 1-2WU
05/28L 6-0LU
05/27L 6-1LU
05/04W 7-2WO
05/03W 4-0WU
05/02W 3-0WU
04/17L 7-2LO

Frequently Asked Questions

What is the Houston Astros vs Seattle Mariners all-time record?
The Houston Astros are 15-7 against the Seattle Mariners in 2022 in head-to-head matchups.
What is the Houston Astros ATS record vs the Seattle Mariners?
The Houston Astros are 11-11-0 against the spread vs the Seattle Mariners in 2022 on DraftKings, with +11.49% ROI.
Do Houston Astros vs Seattle Mariners games go over or under?
Houston Astros vs Seattle Mariners games average 7.3 total points in 2022. The Over has hit 40.91% of the time.

More Astros Matchups

Head-to-head betting record for Houston Astros vs Seattle Mariners in the 2022 season on LineTerminal. The Astros are 15-7 straight up against the Mariners and 11-11-0 against the spread (50% cover rate, +11.49% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

LineTerminal

AI-powered betting intelligence for NBA, NHL, MLB, and NCAAB.

LineTerminal provides sports data and analytics for informational and entertainment purposes only. LineTerminal does not accept, place, or facilitate bets or wagers of any kind. Odds data is sourced from third-party providers and may not reflect exact lines at every sportsbook. Past performance does not guarantee future results. Sports betting involves risk — never wager more than you can afford to lose.

If you or someone you know has a gambling problem, call 1-800-MY-RESET (National Problem Gambling Helpline) or visit ncpgambling.org. Must be 21+ in most jurisdictions. Please gamble responsibly.

© 2026 LineTerminal. All rights reserved.