Boston Red Sox Lead Baltimore Orioles 51-45 in Head-to-Head Matchups

MLB42-34-0 ATS (55.26%)

The Baltimore Orioles are 45-51 against the Boston Red Sox in head-to-head matchups, going 42-34-0 ATS (55.26% cover rate) with +5.12% ROI. Games average 10.3 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official MLB box scores.

See methodology.

Orioles vs Red Sox Betting Record

Against the Spread
42-34-0
Win %
55.26%
ROI
+5.12%
Units
+3.9
Moneyline
42-50-0
Win %
45.65%
ROI
-3.67%
Units
-3.4
Over Rate
34-39-3
Win %
46.58%
ROI
-10.38%
Units
-7.6

From the Other Side — Red Sox vs Orioles

Against the Spread
34-42-0
Win %
44.74%
ROI
-11.37%
Units
-8.6
Moneyline
50-42-0
Win %
54.35%
ROI
-4.34%
Units
-4.0
Over Rate
34-39-3
Win %
46.58%
ROI
-10.38%
Units
-7.6

Venue Splits

Orioles Home
20-16-0 ATS
55.56% • +15.08%
20-26-0 ML (43.48%)
Red Sox Home
18-22-0 ATS
45% • -10.08%
24-22-0 ML (52.17%)

Scoring Averages

Orioles
4.8
PPG
5.5
allowed
Total
10.3
Avg
96
games
Red Sox
5.5
PPG
4.8
allowed

Recent Matchups

DateScoreATSMLO/U
07/22L 6-3LU
07/22W 1-5WU
07/20L 6-5LO
06/04W 2-8WU
06/03L 8-1LO
06/02W 2-4WU
04/26L 3-5LO
04/25L 1-17LO
04/24W 10-3WO
08/28L 2-3LU
08/27L 2-3LU
08/26L 0-5LU
08/25L 3-4LU
08/19W 3-4WU
08/18W 3-6WO
05/25W 1-5WU
05/24W 1-2WU
05/24L 6-5LO
05/23L 19-5LO
04/03L 4-8LO

Frequently Asked Questions

What is the Baltimore Orioles vs Boston Red Sox all-time record?
The Baltimore Orioles are 45-51 against the Boston Red Sox in head-to-head matchups.
What is the Baltimore Orioles ATS record vs the Boston Red Sox?
The Baltimore Orioles are 42-34-0 against the spread vs the Boston Red Sox on DraftKings, with +5.12% ROI.
Do Baltimore Orioles vs Boston Red Sox games go over or under?
Baltimore Orioles vs Boston Red Sox games average 10.3 total points. The Over has hit 46.58% of the time.

More Orioles Matchups

Head-to-head betting record for Baltimore Orioles vs Boston Red Sox on LineTerminal. The Orioles are 45-51 straight up against the Red Sox and 42-34-0 against the spread (55.26% cover rate, +5.12% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

LineTerminal

AI-powered betting intelligence for NBA, WNBA, NHL, MLB, NFL, NCAAB, and NCAAF.

LineTerminal provides sports data and analytics for informational and entertainment purposes only. LineTerminal does not accept, place, or facilitate bets or wagers of any kind. Odds data is sourced from third-party providers and may not reflect exact lines at every sportsbook. Past performance does not guarantee future results. Sports betting involves risk — never wager more than you can afford to lose.

If you or someone you know has a gambling problem, call 1-800-MY-RESET (National Problem Gambling Helpline) or visit ncpgambling.org. Must be 21+ in most jurisdictions. Please gamble responsibly.

© 2026 LineTerminal LLC. All rights reserved.