Indianapolis Colts Lead Tennessee Titans 2-0 in Head-to-Head Matchups (2025-26)

NFL2-0-0 ATS (100%)Updated October 26, 2025

The Indianapolis Colts are 2-0 against the Tennessee Titans in 2025-26 in head-to-head matchups, going 2-0-0 ATS (100% cover rate) with +93.92% ROI. Games average 56.5 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NFL box scores.

See methodology.

Colts vs Titans Betting Record — 2025-26

Against the Spread

2-0-0

Win %

100%

ROI

+93.92%

Units

+1.9

Moneyline

2-0-0

Win %

100%

ROI

+23.13%

Units

+0.5

Over Rate

2-0-0

Win %

100%

ROI

+87.83%

Units

+1.8

From the Other Side — Titans vs Colts

Against the Spread

0-2-0

Win %

ROI

-100%

Units

-2.0

Moneyline

0-2-0

Win %

ROI

-100%

Units

-2.0

Over Rate

2-0-0

Win %

100%

ROI

+87.83%

Units

+1.8

Venue Splits

Colts Home

1-0-0 ATS

100% • +95.24%

1-0-0 ML (100%)

Titans Home

0-1-0 ATS

0% • -100%

0-1-0 ML (0%)

Scoring Averages

Colts

39.5

PPG

allowed

Total

56.5

Avg

games

Titans

PPG

39.5

allowed

Recent Matchups (2025-26)

Date	Matchup	Score	Spread	ATS	ML	O/U
10/262025-10-26	Titans @ Colts	W 38-14	-15.5	✓	W	O
09/212025-09-21	Colts @ Titans	W 20-41	-6	✓	W	O

Frequently Asked Questions

What is the Indianapolis Colts vs Tennessee Titans 2025-26 record?

The Indianapolis Colts are 2-0 against the Tennessee Titans in 2025-26 in head-to-head matchups.

What is the Indianapolis Colts ATS record vs the Tennessee Titans?

The Indianapolis Colts are 2-0-0 against the spread vs the Tennessee Titans in 2025-26 on DraftKings, with +93.92% ROI.

Do Indianapolis Colts vs Tennessee Titans games go over or under?

Indianapolis Colts vs Tennessee Titans games average 56.5 total points in 2025-26. The Over has hit 100% of the time.

More Colts Matchups

vs Texans

vs Jaguars

See from Titans perspective

Head-to-head betting record for Indianapolis Colts vs Tennessee Titans in the 2025-26 season on LineTerminal. The Colts are 2-0 straight up against the Titans and 2-0-0 against the spread (100% cover rate, +93.92% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.