Purdue Boilermakers Lead Indiana Hoosiers 2-1 in Head-to-Head Matchups

NCAAF1-2-0 ATS (33.33%)Updated November 28, 2025

The Purdue Boilermakers are 2-1 against the Indiana Hoosiers in head-to-head matchups, going 1-2-0 ATS (33.33% cover rate) with -36.36% ROI. Games average 57 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Purdue Boilermakers vs Indiana Hoosiers Betting Record

Against the Spread

1-2-0

Win %

33.33%

ROI

-36.36%

Units

-1.1

Moneyline

2-1-0

Win %

66.67%

ROI

-9.75%

Units

-0.3

Over Rate

2-1-0

Win %

66.67%

ROI

+25.41%

Units

+0.8

From the Other Side — Indiana Hoosiers vs Purdue Boilermakers

Against the Spread

2-1-0

Win %

66.67%

ROI

+26.19%

Units

+0.8

Moneyline

1-2-0

Win %

33.33%

ROI

-66%

Units

-2.0

Over Rate

2-1-0

Win %

66.67%

ROI

+25.41%

Units

+0.8

Venue Splits

Purdue Boilermakers Home

0-2-0 ATS

0% • -100%

1-1-0 ML (50%)

Indiana Hoosiers Home

0-1-0 ATS

0% • -100%

0-1-0 ML (0%)

Scoring Averages

Purdue Boilermakers

22.7

PPG

34.3

allowed

Total

Avg

games

Indiana Hoosiers

34.3

PPG

22.7

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
11/282025-11-28	Indiana Hoosiers @ Purdue Boilermakers	L 3-56	-28.5	✗	L	O
11/252023-11-25	Indiana Hoosiers @ Purdue Boilermakers	W 35-31	-6.5	✗	W	O
11/262022-11-26	Purdue Boilermakers @ Indiana Hoosiers	W 16-30	-10	✓	W	U

Frequently Asked Questions

What is the Purdue Boilermakers vs Indiana Hoosiers all-time record?

The Purdue Boilermakers are 2-1 against the Indiana Hoosiers in head-to-head matchups.

What is the Purdue Boilermakers ATS record vs the Indiana Hoosiers?

The Purdue Boilermakers are 1-2-0 against the spread vs the Indiana Hoosiers on DraftKings, with -36.36% ROI.

Do Purdue Boilermakers vs Indiana Hoosiers games go over or under?

Purdue Boilermakers vs Indiana Hoosiers games average 57 total points. The Over has hit 66.67% of the time.

More Purdue Boilermakers Matchups

vs Illinois Fighting Illini

vs Iowa Hawkeyes

vs Maryland Terrapins

vs Michigan State Spartans

vs Michigan Wolverines

vs Minnesota Golden Gophers

See from Indiana Hoosiers perspective

Head-to-head betting record for Purdue Boilermakers vs Indiana Hoosiers on LineTerminal. The Purdue Boilermakers are 2-1 straight up against the Indiana Hoosiers and 1-2-0 against the spread (33.33% cover rate, -36.36% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.