Louisville CardinalsAway52
Duke Blue DevilsHome83SpreadCoverFav -8.5
MoneylineWin
TotalUnder157.5
NCAAB · Head to head
Duke Blue Devils vs Louisville Cardinals
All recorded seasonsLast meeting Jan 26, 2026
Betting comparison
All seasons
Duke Blue Devils
6 bets5-1-1Wins · Losses · Pushes
- Win rate
- 83.33%
- ROI
- +59.15%
- Units
- +3.55u
Louisville Cardinals
6 bets1-5-1Wins · Losses · Pushes
- Win rate
- 16.67%
- ROI
- -68.18%
- Units
- -4.09u
Closing lines · Flat 1u per bet · Methodology
Scoring per game
Average pointsDuke Blue Devils80.3
Louisville Cardinals63.1
Combined143.4
Recent meetings
Bet results from the Duke Blue Devils perspective. Spread values show the favorite’s closing line.
Louisville CardinalsAway52Duke Blue DevilsHome83Duke Blue DevilsAway84Louisville CardinalsHome73SpreadCoverFav -1.5
MoneylineWin
TotalUnder161.5
Louisville CardinalsAway62Duke Blue DevilsHome73SpreadCoverFav -6.5
MoneylineWin
TotalUnder148.5
Duke Blue DevilsAway76Louisville CardinalsHome65SpreadCoverFav -8
MoneylineWin
TotalUnder146.5
Louisville CardinalsAway59Duke Blue DevilsHome84SpreadCoverFav -20
MoneylineWin
TotalUnder151.5
More Duke Blue Devils matchups
About this matchup
What is the Duke Blue Devils vs Louisville Cardinals all-time record?
The Duke Blue Devils are 7-0 against the Louisville Cardinals in head-to-head matchups.
What is the Duke Blue Devils ATS record vs the Louisville Cardinals?
The Duke Blue Devils are 5-1-1 against the spread vs the Louisville Cardinals on DraftKings, with +59.15% ROI.
Do Duke Blue Devils vs Louisville Cardinals games go over or under?
Duke Blue Devils vs Louisville Cardinals games average 143.4 total points. The Over has hit 28.57% of the time.