Padres vs White Sox Betting Record — 2025
Against the Spread
1-2-0
Win %
33.33%
ROI
-36.09%
Units
-1.1
Moneyline
2-1-0
Win %
66.67%
ROI
+2.51%
Units
+0.1
Over Rate
1-2-0
Win %
33.33%
ROI
-36.64%
Units
-1.1
From the Other Side — White Sox vs Padres
Against the Spread
2-1-0
Win %
66.67%
ROI
+26.9%
Units
+0.8
Moneyline
1-2-0
Win %
33.33%
ROI
-14.33%
Units
-0.4
Over Rate
1-2-0
Win %
33.33%
ROI
-36.64%
Units
-1.1
Venue Splits
Padres Home
White Sox Home
2-1-0 ATS
66.67% • +26.9%
1-2-0 ML (33.33%)
Scoring Averages
Padres
4.3
PPG
3
allowed
Total
7.3
Avg
3
games
White Sox
3
PPG
4.3
allowed
Recent Matchups (2025)
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 09/212025-09-21 | W 2-3 | ✗ | W | U |
| 09/202025-09-20 | W 3-7 | ✓ | W | O |
| 09/192025-09-19 | L 4-3 | ✗ | L | U |
Frequently Asked Questions
What is the San Diego Padres vs Chicago White Sox all-time record?
The San Diego Padres are 2-1 against the Chicago White Sox in 2025 in head-to-head matchups.
What is the San Diego Padres ATS record vs the Chicago White Sox?
The San Diego Padres are 1-2-0 against the spread vs the Chicago White Sox in 2025 on DraftKings, with -36.09% ROI.
Do San Diego Padres vs Chicago White Sox games go over or under?
San Diego Padres vs Chicago White Sox games average 7.3 total points in 2025. The Over has hit 33.33% of the time.

Inside Edge
