White Sox vs Padres Betting Record — 2025
Against the Spread
2-1-0
Win %
66.67%
ROI
+26.9%
Units
+0.8
Moneyline
1-2-0
Win %
33.33%
ROI
-14.33%
Units
-0.4
Over Rate
1-2-0
Win %
33.33%
ROI
-36.64%
Units
-1.1
From the Other Side — Padres vs White Sox
Against the Spread
1-2-0
Win %
33.33%
ROI
-36.09%
Units
-1.1
Moneyline
2-1-0
Win %
66.67%
ROI
+2.51%
Units
+0.1
Over Rate
1-2-0
Win %
33.33%
ROI
-36.64%
Units
-1.1
Venue Splits
White Sox Home
2-1-0 ATS
66.67% • +26.9%
1-2-0 ML (33.33%)
Padres Home
Scoring Averages
White Sox
3
PPG
4.3
allowed
Total
7.3
Avg
3
games
Padres
4.3
PPG
3
allowed
Recent Matchups (2025)
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 09/212025-09-21 | L 2-3 | ✓ | L | U |
| 09/202025-09-20 | L 3-7 | ✗ | L | O |
| 09/192025-09-19 | W 4-3 | ✓ | W | U |
Frequently Asked Questions
What is the Chicago White Sox vs San Diego Padres all-time record?
The Chicago White Sox are 1-2 against the San Diego Padres in 2025 in head-to-head matchups.
What is the Chicago White Sox ATS record vs the San Diego Padres?
The Chicago White Sox are 2-1-0 against the spread vs the San Diego Padres in 2025 on DraftKings, with +26.9% ROI.
Do Chicago White Sox vs San Diego Padres games go over or under?
Chicago White Sox vs San Diego Padres games average 7.3 total points in 2025. The Over has hit 33.33% of the time.

Inside Edge
