San Diego Padres Lead Chicago White Sox 9-3 in Head-to-Head Matchups

MLB7-5-0 ATS (58.33%)Data through 2025-09-21

White Sox vs Padres Betting Record

Against the Spread
7-5-0
Win %
58.33%
ROI
+10.8%
Units
+1.3
Moneyline
3-9-0
Win %
25%
ROI
-34.83%
Units
-4.2
Over Rate
1-9-2
Win %
10%
ROI
-80.99%
Units
-8.1

From the Other Side — Padres vs White Sox

Against the Spread
5-7-0
Win %
41.67%
ROI
-26.42%
Units
-3.2
Moneyline
9-3-0
Win %
75%
ROI
+14.49%
Units
+1.7
Over Rate
1-9-2
Win %
10%
ROI
-80.99%
Units
-8.1

Venue Splits

White Sox Home
4-2-0 ATS
66.67% • +29.8%
1-5-0 ML (16.67%)
Padres Home
3-3-0 ATS
50% • -18.96%
4-2-0 ML (66.67%)

Scoring Averages

White Sox
2.2
PPG
3.7
allowed
Total
5.8
Avg
12
games
Padres
3.7
PPG
2.2
allowed

Recent Matchups

DateScoreATSMLO/U
09/21L 2-3LU
09/20L 3-7LO
09/19W 4-3WU
09/22L 4-2LU
09/21L 6-2LP
09/20L 3-2LU
10/01L 1-2LU
09/30L 1-6LU
09/29L 2-3LU
10/02W 1-2WU
10/01L 5-2LP
09/30W 1-3WU

Frequently Asked Questions

What is the Chicago White Sox vs San Diego Padres all-time record?
The Chicago White Sox are 3-9 against the San Diego Padres in head-to-head matchups.
What is the Chicago White Sox ATS record vs the San Diego Padres?
The Chicago White Sox are 7-5-0 against the spread vs the San Diego Padres on DraftKings, with +10.8% ROI.
Do Chicago White Sox vs San Diego Padres games go over or under?
Chicago White Sox vs San Diego Padres games average 5.8 total points. The Over has hit 10% of the time.

More White Sox Matchups

Head-to-head betting record for Chicago White Sox vs San Diego Padres on LineTerminal. The White Sox are 3-9 straight up against the Padres and 7-5-0 against the spread (58.33% cover rate, +10.8% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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