San Diego Padres Lead Chicago White Sox 9-3 in Head-to-Head Matchups

MLB5-7-0 ATS (41.67%)Data through 2025-09-21

Padres vs White Sox Betting Record

Against the Spread
5-7-0
Win %
41.67%
ROI
-26.42%
Units
-3.2
Moneyline
9-3-0
Win %
75%
ROI
+14.49%
Units
+1.7
Over Rate
1-9-2
Win %
10%
ROI
-80.99%
Units
-8.1

From the Other Side — White Sox vs Padres

Against the Spread
7-5-0
Win %
58.33%
ROI
+10.8%
Units
+1.3
Moneyline
3-9-0
Win %
25%
ROI
-34.83%
Units
-4.2
Over Rate
1-9-2
Win %
10%
ROI
-80.99%
Units
-8.1

Venue Splits

Padres Home
3-3-0 ATS
50% • -18.96%
4-2-0 ML (66.67%)
White Sox Home
4-2-0 ATS
66.67% • +29.8%
1-5-0 ML (16.67%)

Scoring Averages

Padres
3.7
PPG
2.2
allowed
Total
5.8
Avg
12
games
White Sox
2.2
PPG
3.7
allowed

Recent Matchups

DateScoreATSMLO/U
09/21W 2-3WU
09/20W 3-7WO
09/19L 4-3LU
09/22W 4-2WU
09/21W 6-2WP
09/20W 3-2WU
10/01W 1-2WU
09/30W 1-6WU
09/29W 2-3WU
10/02L 1-2LU
10/01W 5-2WP
09/30L 1-3LU

Frequently Asked Questions

What is the San Diego Padres vs Chicago White Sox all-time record?
The San Diego Padres are 9-3 against the Chicago White Sox in head-to-head matchups.
What is the San Diego Padres ATS record vs the Chicago White Sox?
The San Diego Padres are 5-7-0 against the spread vs the Chicago White Sox on DraftKings, with -26.42% ROI.
Do San Diego Padres vs Chicago White Sox games go over or under?
San Diego Padres vs Chicago White Sox games average 5.8 total points. The Over has hit 10% of the time.

More Padres Matchups

Head-to-head betting record for San Diego Padres vs Chicago White Sox on LineTerminal. The Padres are 9-3 straight up against the White Sox and 5-7-0 against the spread (41.67% cover rate, -26.42% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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