Milwaukee Brewers Lead Chicago Cubs 14-4 in Head-to-Head Matchups (2021)

MLB5-1-0 ATS (83.33%)Data through 2021-09-19

Brewers vs Cubs Betting Record — 2021

Against the Spread
5-1-0
Win %
83.33%
ROI
+50.8%
Units
+3.0
Moneyline
12-3-0
Win %
80%
ROI
+26.04%
Units
+3.9
Over Rate
5-0-1
Win %
100%
ROI
+95.41%
Units
+4.8

From the Other Side — Cubs vs Brewers

Against the Spread
1-5-0
Win %
16.67%
ROI
-68.18%
Units
-4.1
Moneyline
3-12-0
Win %
20%
ROI
-55.86%
Units
-8.4
Over Rate
5-0-1
Win %
100%
ROI
+95.41%
Units
+4.8

Venue Splits

Brewers Home
2-1-0 ATS
66.67% • +17.3%
7-2-0 ML (77.78%)
Cubs Home
0-3-0 ATS
0% • -100%
1-5-0 ML (16.67%)

Scoring Averages

Brewers
6.7
PPG
3.6
allowed
Total
10.3
Avg
18
games
Cubs
3.6
PPG
6.7
allowed

Recent Matchups (2021)

DateScoreATSMLO/U
09/19L 4-6LO
09/18W 6-4WO
09/17W 8-5WO
08/12W 4-17WO
08/11W 0-10WP
08/10W 3-6WO
06/30W 15-7-W-
06/29W 2-1-W-
06/28W 14-4-W-
04/25W 0-6-W-
04/24W 3-4-W-
04/23L 15-2-L-
04/14W 7-0-W-
04/13L 2-3-L-
04/12W 6-3-W-
04/07W 2-4---
04/06W 0-4---
04/05L 5-3---

Frequently Asked Questions

What is the Milwaukee Brewers vs Chicago Cubs all-time record?
The Milwaukee Brewers are 14-4 against the Chicago Cubs in 2021 in head-to-head matchups.
What is the Milwaukee Brewers ATS record vs the Chicago Cubs?
The Milwaukee Brewers are 5-1-0 against the spread vs the Chicago Cubs in 2021 on DraftKings, with +50.8% ROI.
Do Milwaukee Brewers vs Chicago Cubs games go over or under?
Milwaukee Brewers vs Chicago Cubs games average 10.3 total points in 2021. The Over has hit 100% of the time.

More Brewers Matchups

Head-to-head betting record for Milwaukee Brewers vs Chicago Cubs in the 2021 season on LineTerminal. The Brewers are 14-4 straight up against the Cubs and 5-1-0 against the spread (83.33% cover rate, +50.8% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

LineTerminal

AI-powered betting intelligence for NBA, NHL, MLB, and NCAAB.

LineTerminal provides sports data and analytics for informational and entertainment purposes only. LineTerminal does not accept, place, or facilitate bets or wagers of any kind. Odds data is sourced from third-party providers and may not reflect exact lines at every sportsbook. Past performance does not guarantee future results. Sports betting involves risk — never wager more than you can afford to lose.

If you or someone you know has a gambling problem, call 1-800-MY-RESET (National Problem Gambling Helpline) or visit ncpgambling.org. Must be 21+ in most jurisdictions. Please gamble responsibly.

© 2026 LineTerminal. All rights reserved.