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San Diego Padres Lead Pittsburgh Pirates 5-1 in Head-to-Head Matchups (2025)

MLB3-3-0 ATS (50%)

The San Diego Padres are 5-1 against the Pittsburgh Pirates in 2025 in head-to-head matchups, going 3-3-0 ATS (50% cover rate) with +16.83% ROI. Games average 6.7 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official MLB box scores.

See methodology.

Padres vs Pirates Betting Record — 2025

Against the Spread
3-3-0
Win %
50%
ROI
+16.83%
Units
+1.0
Moneyline
5-1-0
Win %
83.33%
ROI
+46.49%
Units
+2.8
Over Rate
2-4-0
Win %
33.33%
ROI
-37.35%
Units
-2.2

From the Other Side — Pirates vs Padres

Against the Spread
3-3-0
Win %
50%
ROI
-15.67%
Units
-0.9
Moneyline
1-5-0
Win %
16.67%
ROI
-54.17%
Units
-3.3
Over Rate
2-4-0
Win %
33.33%
ROI
-37.35%
Units
-2.2

Venue Splits

Padres Home
1-2-0 ATS
33.33% • -21.67%
2-1-0 ML (66.67%)
Pirates Home
1-2-0 ATS
33.33% • -48.15%
0-3-0 ML (0%)

Scoring Averages

Padres
4
PPG
2.7
allowed
Total
6.7
Avg
6
games
Pirates
2.7
PPG
4
allowed

Recent Matchups (2025)

DateScoreATSMLO/U
06/01W 6-4WO
05/31L 0-5LU
05/30W 3-2WU
05/04W 0-4WU
05/03W 1-2WU
05/02W 4-9WO

Frequently Asked Questions

What is the San Diego Padres vs Pittsburgh Pirates 2025 record?
The San Diego Padres are 5-1 against the Pittsburgh Pirates in 2025 in head-to-head matchups.
What is the San Diego Padres ATS record vs the Pittsburgh Pirates?
The San Diego Padres are 3-3-0 against the spread vs the Pittsburgh Pirates in 2025 on DraftKings, with +16.83% ROI.
Do San Diego Padres vs Pittsburgh Pirates games go over or under?
San Diego Padres vs Pittsburgh Pirates games average 6.7 total points in 2025. The Over has hit 33.33% of the time.

More Padres Matchups

Head-to-head betting record for San Diego Padres vs Pittsburgh Pirates in the 2025 season on LineTerminal. The Padres are 5-1 straight up against the Pirates and 3-3-0 against the spread (50% cover rate, +16.83% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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