White Sox vs Cubs Betting Record — 2025
Against the Spread
2-4-0
Win %
33.33%
ROI
-37.57%
Units
-2.3
Moneyline
1-5-0
Win %
16.67%
ROI
-58%
Units
-3.5
Over Rate
4-1-1
Win %
80%
ROI
+51.31%
Units
+2.6
From the Other Side — Cubs vs White Sox
Against the Spread
4-2-0
Win %
66.67%
ROI
+19.93%
Units
+1.2
Moneyline
5-1-0
Win %
83.33%
ROI
+20.37%
Units
+1.2
Over Rate
4-1-1
Win %
80%
ROI
+51.31%
Units
+2.6
Venue Splits
White Sox Home
2-1-0 ATS
66.67% • +24.85%
1-2-0 ML (33.33%)
Cubs Home
3-0-0 ATS
100% • +77.53%
3-0-0 ML (100%)
Scoring Averages
White Sox
4.2
PPG
7
allowed
Total
11.2
Avg
6
games
Cubs
7
PPG
4.2
allowed
Recent Matchups (2025)
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 07/272025-07-27 | L 4-5 | ✓ | L | O |
| 07/262025-07-26 | L 1-6 | ✗ | L | U |
| 07/252025-07-25 | W 12-5 | ✓ | W | O |
| 05/182025-05-18 | L 6-2 | ✗ | L | O |
| 05/172025-05-17 | L 7-3 | ✗ | L | P |
| 05/162025-05-16 | L 13-3 | ✗ | L | O |
Frequently Asked Questions
What is the Chicago White Sox vs Chicago Cubs all-time record?
The Chicago White Sox are 1-5 against the Chicago Cubs in 2025 in head-to-head matchups.
What is the Chicago White Sox ATS record vs the Chicago Cubs?
The Chicago White Sox are 2-4-0 against the spread vs the Chicago Cubs in 2025 on DraftKings, with -37.57% ROI.
Do Chicago White Sox vs Chicago Cubs games go over or under?
Chicago White Sox vs Chicago Cubs games average 11.2 total points in 2025. The Over has hit 80% of the time.

Inside Edge
