Chicago White Sox Lead Boston Red Sox 17-15 in Head-to-Head Matchups

MLB16-13-0 ATS (55.17%)Data through 2025-04-21

White Sox vs Red Sox Betting Record

Against the Spread
16-13-0
Win %
55.17%
ROI
+5.41%
Units
+1.6
Moneyline
17-15-0
Win %
53.13%
ROI
+19.08%
Units
+6.1
Over Rate
11-18-0
Win %
37.93%
ROI
-28.97%
Units
-8.4

From the Other Side — Red Sox vs White Sox

Against the Spread
13-16-0
Win %
44.83%
ROI
-16.02%
Units
-4.6
Moneyline
15-17-0
Win %
46.88%
ROI
-21.74%
Units
-7.0
Over Rate
11-18-0
Win %
37.93%
ROI
-28.97%
Units
-8.4

Venue Splits

White Sox Home
7-9-0 ATS
43.75% • -18.67%
9-7-0 ML (56.25%)
Red Sox Home
4-9-0 ATS
30.77% • -43.92%
8-8-0 ML (50%)

Scoring Averages

White Sox
4
PPG
4.6
allowed
Total
8.6
Avg
32
games
Red Sox
4.6
PPG
4
allowed

Recent Matchups

DateScoreATSMLO/U
04/21L 4-2LU
04/20W 4-8WO
04/19L 4-3LU
04/18L 10-3LO
04/13L 1-3LU
04/12W 3-2WU
04/11W 11-1WO
09/08W 2-7WU
09/07L 7-5LO
09/06L 3-1LU
06/09L 4-6LO
06/08W 6-1WU
06/07W 7-2WO
06/06L 2-14LO
09/24W 2-3WU
09/23W 0-1WU
09/22L 3-2LU
06/25W 4-1WU
06/24W 5-4WO
06/23L 1-3LU

Frequently Asked Questions

What is the Chicago White Sox vs Boston Red Sox all-time record?
The Chicago White Sox are 17-15 against the Boston Red Sox in head-to-head matchups.
What is the Chicago White Sox ATS record vs the Boston Red Sox?
The Chicago White Sox are 16-13-0 against the spread vs the Boston Red Sox on DraftKings, with +5.41% ROI.
Do Chicago White Sox vs Boston Red Sox games go over or under?
Chicago White Sox vs Boston Red Sox games average 8.6 total points. The Over has hit 37.93% of the time.

More White Sox Matchups

Head-to-head betting record for Chicago White Sox vs Boston Red Sox on LineTerminal. The White Sox are 17-15 straight up against the Red Sox and 16-13-0 against the spread (55.17% cover rate, +5.41% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

LineTerminal

AI-powered betting intelligence for NBA, NHL, MLB, and NCAAB.

LineTerminal provides sports data and analytics for informational and entertainment purposes only. LineTerminal does not accept, place, or facilitate bets or wagers of any kind. Odds data is sourced from third-party providers and may not reflect exact lines at every sportsbook. Past performance does not guarantee future results. Sports betting involves risk — never wager more than you can afford to lose.

If you or someone you know has a gambling problem, call 1-800-MY-RESET (National Problem Gambling Helpline) or visit ncpgambling.org. Must be 21+ in most jurisdictions. Please gamble responsibly.

© 2026 LineTerminal. All rights reserved.