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New York Yankees Lead Chicago White Sox 21-10 in Head-to-Head Matchups

MLB18-10-0 ATS (64.29%)Data through 2025-09-25

Yankees vs White Sox Betting Record

Against the Spread

18-10-0

Win %

64.29%

ROI

+14.1%

Units

+4.0

Moneyline

21-10-0

Win %

67.74%

ROI

+8.5%

Units

+2.6

Over Rate

13-15-0

Win %

46.43%

ROI

-11.12%

Units

-3.1

From the Other Side — White Sox vs Yankees

Against the Spread

10-18-0

Win %

35.71%

ROI

-33.09%

Units

-9.3

Moneyline

10-21-0

Win %

32.26%

ROI

-22.62%

Units

-7.0

Over Rate

13-15-0

Win %

46.43%

ROI

-11.12%

Units

-3.1

Venue Splits

Yankees Home

6-5-0 ATS

54.55% • -7.47%

10-4-0 ML (71.43%)

White Sox Home

5-12-0 ATS

29.41% • -40.81%

6-11-0 ML (35.29%)

Scoring Averages

Yankees

5.4

PPG

3.6

allowed

Total

9

Avg

31

games

White Sox

3.6

PPG

5.4

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
09/252025-09-25	White Sox @ Yankees	W 5-3	-1.5	✓	W	U
09/242025-09-24	White Sox @ Yankees	W 8-1	-1.5	✓	W	O
09/232025-09-23	White Sox @ Yankees	W 3-2	-1.5	✗	W	U
08/312025-08-31	Yankees @ White Sox	L 3-2	-1.5	✗	L	U
08/302025-08-30	Yankees @ White Sox	W 3-5	-1.5	✓	W	U
08/292025-08-29	Yankees @ White Sox	W 2-10	-1.5	✓	W	O
08/282025-08-28	Yankees @ White Sox	W 4-10	-1.5	✓	W	O
08/142024-08-14	Yankees @ White Sox	W 2-10	-1.5	✓	W	O
08/132024-08-13	Yankees @ White Sox	W 1-4	-1.5	✓	W	U
08/122024-08-12	Yankees @ White Sox	L 12-2	-1.5	✗	L	O
05/192024-05-19	White Sox @ Yankees	W 7-2	-1.5	✓	W	O
05/182024-05-18	White Sox @ Yankees	W 6-1	-1.5	✓	W	U
05/172024-05-17	White Sox @ Yankees	W 4-2	-1.5	✓	W	U
08/092023-08-09	Yankees @ White Sox	L 9-2	-1.5	✗	L	O
08/082023-08-08	Yankees @ White Sox	W 1-7	-1.5	✓	W	U
08/072023-08-07	Yankees @ White Sox	L 5-1	-1.5	✗	L	U
06/082023-06-08	White Sox @ Yankees	L 5-6	-1.5	✗	L	O
06/062023-06-06	White Sox @ Yankees	L 2-3	-1.5	✗	L	U
05/222022-05-22	White Sox @ Yankees	L 0-5	-1.5	✗	L	U
05/222022-05-22	White Sox @ Yankees	L 1-3	-1.5	✗	L	U

Frequently Asked Questions

What is the New York Yankees vs Chicago White Sox all-time record?

The New York Yankees are 21-10 against the Chicago White Sox in head-to-head matchups.

What is the New York Yankees ATS record vs the Chicago White Sox?

The New York Yankees are 18-10-0 against the spread vs the Chicago White Sox on DraftKings, with +14.1% ROI.

Do New York Yankees vs Chicago White Sox games go over or under?

New York Yankees vs Chicago White Sox games average 9 total points. The Over has hit 46.43% of the time.

More Yankees Matchups

See from White Sox perspective

Head-to-head betting record for New York Yankees vs Chicago White Sox on LineTerminal. The Yankees are 21-10 straight up against the White Sox and 18-10-0 against the spread (64.29% cover rate, +14.1% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.