Minnesota Twins Lead Houston Astros 4-3 in Head-to-Head Matchups (2021)

MLB3-1-0 ATS (75%)Data through 2021-08-08

Twins vs Astros Betting Record — 2021

Against the Spread
3-1-0
Win %
75%
ROI
+43.21%
Units
+1.7
Moneyline
4-3-0
Win %
57.14%
ROI
+45.3%
Units
+3.2
Over Rate
1-2-1
Win %
33.33%
ROI
-34.92%
Units
-1.1

From the Other Side — Astros vs Twins

Against the Spread
1-3-0
Win %
25%
ROI
-55%
Units
-2.2
Moneyline
3-4-0
Win %
42.86%
ROI
-32.56%
Units
-2.3
Over Rate
1-2-1
Win %
33.33%
ROI
-34.92%
Units
-1.1

Venue Splits

Twins Home
1-2-0 ML (33.33%)
Astros Home
1-3-0 ATS
25% • -55%
1-3-0 ML (25%)

Scoring Averages

Twins
4.1
PPG
5.4
allowed
Total
9.6
Avg
7
games
Astros
5.4
PPG
4.1
allowed

Recent Matchups (2021)

DateScoreATSMLO/U
08/08W 5-7WO
08/07L 4-0LU
08/06W 4-5WP
08/05W 3-5WU
06/13L 3-14-L-
06/12W 5-2-W-
06/11L 4-6-L-

Frequently Asked Questions

What is the Minnesota Twins vs Houston Astros all-time record?
The Minnesota Twins are 4-3 against the Houston Astros in 2021 in head-to-head matchups.
What is the Minnesota Twins ATS record vs the Houston Astros?
The Minnesota Twins are 3-1-0 against the spread vs the Houston Astros in 2021 on DraftKings, with +43.21% ROI.
Do Minnesota Twins vs Houston Astros games go over or under?
Minnesota Twins vs Houston Astros games average 9.6 total points in 2021. The Over has hit 33.33% of the time.

More Twins Matchups

Head-to-head betting record for Minnesota Twins vs Houston Astros in the 2021 season on LineTerminal. The Twins are 4-3 straight up against the Astros and 3-1-0 against the spread (75% cover rate, +43.21% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

LineTerminal

AI-powered betting intelligence for NBA, NHL, MLB, and NCAAB.

LineTerminal provides sports data and analytics for informational and entertainment purposes only. LineTerminal does not accept, place, or facilitate bets or wagers of any kind. Odds data is sourced from third-party providers and may not reflect exact lines at every sportsbook. Past performance does not guarantee future results. Sports betting involves risk — never wager more than you can afford to lose.

If you or someone you know has a gambling problem, call 1-800-MY-RESET (National Problem Gambling Helpline) or visit ncpgambling.org. Must be 21+ in most jurisdictions. Please gamble responsibly.

© 2026 LineTerminal. All rights reserved.