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Home/MLB Schedule/Guardians @ Twins

Guardians 2, Twins 6 — Sep 21, 2025 Recap

Minnesota Twins beat Cleveland Guardians 2-6 on Sep 21, 2025.

Played September 21, 2025

Game FAQ — score, spread, and total

Who won Cleveland Guardians vs Minnesota Twins on Sep 21, 2025?

Minnesota Twins won 2-6 on Sep 21, 2025.

See methodology for grading rules and ROI calculation.

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